Effect of thyroid hormone on prognosis of patients with type A aortic dissection
MA Rui
WANG Xiao-min
CHEN Jing
DONG Lei
Abstract：Objective To investigate the impact of thyroid hormones on the prognosis of patients with type A aortic dissection.Methods 390 patients who underwent surgery for type A aortic dissection at Shanghai Changhai Hospital from January 2010 to December 2022 were selected and categorized into the dead group and the surviving group based on the survival outcome.The influence of thyroid hormones on mortality rate was assessed.Results The average age of the patients was(52.1±13.0)years,with 79.7％being male;66.9％had hypertension,and 39.5％had renal insufficiency.The mean duration of cardiopulmonary bypass during the surgery was(144.0±39.8)minutes,and the average postoperative hospital stay was(24.4±16.9)days.There were 57 deaths in the dead group and 333 in the surviving group,resulting in a mortality rate of 14.6％.Significant differences were observed in the FT3 and FT4 between the two groups(P＜0.05).The higher the levels of FT3(OR=0.834,P＜0.001)and FT4(OR=0.982,P=0.003),the lower the fatality rate.Conclusion FT3 and FT4 would be the important prognostic factors in patients with type A aortic dissection.
Keywords：Thyroid hormoneType A aortic dissectionHeart surgery
Publication Date：2024-08-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 735-738 )