Predictive significance of the ratio of fibrinogen to albumin in delayed recovery after cardiac valve surgery in adults

LI Liu-yuan; ZHANG Chong-jian; CHEN Miao-yun; LUO Dan-dong; CHEN Ji-mei; LI Xiao-feng

doi:10.3969/j.issn.1672-5301.2024.07.004

Abstract：Objective To evaluate the association between the preoperative ratio of fibrinogen to albumin(FAR)and postoperative delayed recovery in adult patients underwent cardiac valve surgery.Methods The clinical data of adult patients who underwent cardiac valve surgery at Guangdong Provincial People's Hospital from January to June 2019 were collected.A total of 234 patients were included.The patients were categorized into three groups based on preoperative FAR values:the group low(FAR＜7.274,78 patients),the group middle(7.274≤FAR≤9.064,78 patients)and the group high(FAR＞9.064,78 patients).Univariate and multivariate logistic regression and receiver operating characteristic curve were used to explore the association between FAR and delayed recovery.Results Multivariate logistic regression analysis showed that the risk of delayed recovery increased by 138％for every one standard deviation increase in the FAR(OR=2.38,P＜0.001).The risk of delayed recovery in the group high was 3.76 times higher than that of the group low(OR=3.76,P=0.002).The risk of prolonged mechanical ventilation in the group high was 2.60 times higher than that in the group low(OR=2.6,P=0.046).The risk of prolonged hospital stay in the group high was 3.49 times higher than that of the group low(OR=3.49,P=0.008).There was a linear relationship between preoperative FAR and postoperative delayed recovery(P＞0.05).The risk of delayed recovery increased with preoperative FAR(P＜0.001).Conclusion The preoperative FAR could effectively predict the occurrence of postoperative delayed recovery in adults after cardiac valve surgery.