The role of pyroptosis in chronic heart failure
PAN Jia-xi
ZHONG Jiang-hua
Abstract：Pyroptosis is a type of programmed cell death accompanied by an inflammatory,whose features are the formation of membrane pores on the cytoplasmic membrane,release of pro-inflammatory factors and cell contents,and swelling and rapid rupture of cells.Recent studies have suggested that pyroptosis is closely related with chronic heart failure(CHF),therefore,targeting pyroptosis has a good prospect in alleviating CHF.This paper reviews signaling pathways of pyroptosis and the role of pyroptosis in CHF as well as therapeutic targets associated with pyroptosis.
Keywords：PyroptosisChronic heart failureSignaling pathway
Publication Date：2024-01-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 24-28 )