Relationship between bulbar conjunctival morphology and coronary artery disease

MA Jing; LI Zi-ning; JIAO Qian; SUN Di; LI Hai-xia

doi:10.3969/j.issn.1672-5301.2023.12.002

Abstract：Objective To investigate the relationship between bulbar conjunctival morphology and coronary atherosclerotic heart disease.Methods From September 1,2021 to April 1,2023,90 patients diagnosed with coronary atherosclerotic heart disease and 94 patients without cardiovascular diseases in the outpatient department of Guang'anmen Hospital,China Academy of Chinese Medical Sciences were continuously enrolled.The bulbar conjunctiva features were collected by a device for diagnosing diseases through the eyes and the clinical data of the subjects were recordedt.The counting differences of bulbar conjunctival morphology and blood vessel counts after bulbar conjunctival partition were analyzed between the two groups,and the correlation analysis was conducted for the differences.Results Compared with the subjects without cardiovascular related diseases,the number of"hill",one of the bulbar conjunctival forms,was significantly increased in the patients with coronary atherosclerotic disease[(2.09±2.04)vs.(0.82±1.44),P<0.05];the number of"blood vessels",one of the bulbar conjunctival forms,in F zone was significantly increased in the patients with coronary atherosclerotic disease[blood vessels in F zone:(2.92±1.77)vs.(2.30±1.52),P<0.05]after the bulbar conjunctival partition.The correlation analysis of various influencing factors showed that there was a positive correlation between the bulbar conjunctival morphology"hill"and coronary atherosclerotic disease.[r=0.441,P<0.01].Conclusion The bulbar conjunctival morphology and the microcirculation of the bulbar conjunctiva are closely related with coronary atherosclerotic heart disease,especially the number of bulbar conjunctival palpebral fissures and the number of intraocular canthal neovascularization.