Coronary slow flow is associated with depression and anxiety of patients
WANG Bin
SI Rui
XIN Yi
CHANG Kuai-le
CHENG Kang
Abstract：Objective To investigate the relationship between coronary slow flow (CSF) and anxiety/depression. Methods 73 patients with CSF confirmed and 73 patients with normal coronary flow (NCF) confirmed by coronary angiography were enrolled in this study. Both groups were examined by Hamilton Anxiety and Depression Score. Results Two groups had comparable baseline characteristics. The HAMA score of CSF group was significantly higher than that of NCF group ( 17.59±4.82 vs. 10.67±3.79，P＜0.05).The HAMD score of CSF group was significantly higher than that of NCF group ( 23.02±6.01 vs. 11.68±4.09，P＜0.05).The level of Hcy in CSF group was significantly higher than that in NCF group[(16.91±4.78) μmol/L vs.(10.53±3.71) μmol/L, P＜0.05] .The level of LP-PLA2 in CSF group was significantly higher than that in NCF group[( 257.9±57.94 ) ng/ml vs.(181.25±45.06 ) ng/ml, P＜0.05].Pearson correlation analysis showed that HAMA was positively correlated with coronary flow velocity of CSF ( r=0.71，P＜0.05)and HAMD was positively correlated with coronary flow velocity of CSF ( r=0.86，P＜0.05).Conclusion There is a significant correlation between CSF and anxiety and depression. Anxiety and depression may be involved in the occurrence of coronary slow blood flow.
Keywords：Coronary slow flowAnxietyDepressionCorrelation
Publication Date：2019-10-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 920-923 )