Study of the relationship between hypothyroidism and the severity of coronary artery lesions in pre-menopausal women
Abstract：Objective To investigate the correlation between hypothyroidism and the severity of coronary artery lesions in premenopausal women. Methods 521 consecutive suspected premenopausal female patients with coronary artery disease(CAD)who undergone coronary angiography(CAG)were selected. The patients were divid-ed into two groups based on thyroid function prior to CAG:hypothyroidism group(43 patients)and euthyroidism group(478 patients). All the patients underwent elective CAG,then the severity of coronary artery lesions was as-sessed by the Gensini scores,and the result of thrombolysis in myocardial infarction(TIMI)was also analyzed. Results Compared with euthyroidism group,the incidence rate of CAD in hypothyroidism group was significantly higher than that in euthyroidism group(76.7% vs. 55.9%,P<0.01),the severity of coronary artery lesions was greater(proportion of severe patients:35.9% vs. 18.8%,P<0.01),the incidence rate of slow blood flow was sig-nificantly higher(18.6% vs. 2.7%,P<0.01). Conclusion Hypothyroidism may be an risk factor in premenopausal women with CAD,which has a higher incidence rate of CAD,an increase in the severity of coronary artery le-sions,and was prone to have slow blood flow.
Keywords：Coronary artery diseasePremenopausal womenHypothyroidismCoronary angiography
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 349-352 )