Predictive value of neutrophil to lymphocyte ratio in patients with acute ST-segment elevation myocardial infarction after percutaneous coronary intervention
Abstract：Objective To investigate the value of neutrophil to lymphocyte ratio(NLR)to predict the prognosis of patients with ST-segment elevation myocardial infarction(STEMI)after percutaneous coronary inter-vention(PCI). Methods A total of 405 patients with STEMI were included in the study. According to the NLR level,patients were divided into high NLR group(NLR≥3.40)and low NLR group(NLR<3.40). Results The age(P=0.078),glucose(P<0.01),white blood cell(WBC)count(P<0.01)and blood urea nitrogen(BUN)(P=0.005)in the high NLR group were higher than those in the low NLR group,and the left ventricular ejection frac-tion(LVEF)(P=0.002)was lower. The incidence of acute heart failure(P=0.017)and ventricular fibrillation(P=0.027)was significantly higher than that of low NLR group during hospitalization. Mortality(P=0.037),nonfatal myocardial infarction(P=0.020),narrow in-stent(P=0.022),the incidence of MACE was significantly higher than the low NLR group during the long-term. Binary logistic regression analysis showed that hypertension,dyslipidemi-a,LVEF and NLR were independent risk factors of MACE in-hospital and long-term, all of them were P<0.05;ROC curve showed AUC 0.649(95%CI 0.540-0.759). Conclusion NLR is an independent predictor for in-hos-pital and long-term prognosis of patients with STEMI.
Keywords：Acute ST-segment elevation myocardial infarctionPercutaneous coronary interventionNeutrophil to lymphocyte ratioPrognosis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 319-323 )