Risk factors for venous thromboembolism in hospitalized patients

doi:10.3969/j.issn.1672-5301.2018.03.011

Abstract：Objective To investigate the risk factors of venous thromboembolism (VTE) through analyze risk factors for patients with VTE during hospitalization.To explore the effectiveness of Caprini risk assessment model in assessing VTE risk in hospitalized patients.Methods 287 patients diagnosed as VTE during hospitalization in Meitan General Hospital and Chaoyang Hospital from January 1,2012 to December 31,2012 were enrolled.The general clinical data,risk factor for VTE,laboratory examination and imaging data were collected and analyzed.The relationship between VTE and risk factors was analyzed.The risk of VTE was evaluated by using the Caprini risk assessment model.The recurrence of VTE and survival states during follow-up were collected.Results (1)Of the 287 patients,92 (32.1％) patients with DVT,93 (32.4％) patients with PTE,102 (35.5％) patients with DVT and PTE.155 were intern medicine patients,and 132 were surgical patients.(2)The risk factors of VTE in the top five were:BMI＞25 kg/m2(63.2％),Protein C or protein S deficiency(52.4％),serum hyperhomocysteinemia (50％),long-term bed-ridden (47.4％),severe lung disease in 132 patients (46％).(3)Caprini model was more effective in evaluate the risk of VTE in surgery patients than medicine patients and the differences were statistically significant (average risk score,7.84±3.45 vs.6.68±3.27,P=0.004).(4)48 cases were found recurrent VTE during follow-up,the recurrence rate was 18.5％.The highest (29.0％) recurrence rate occurred in very high-risk patients,secondly was in high-risk patients (6.5％) and low risk patients had no VTE recurrence.The survival curves showed compared with the other three groups,recurrent VTE in patients at high risk was the highest,and the difference was statistically significant (P=0.021).Conclusion (1)The risk factors of VTE for inpatients are:BMI＞25 kg/m2,Protein C or protein S deficiency,hyperhomocysteinemia,long-term bed-ridden,severe lung disease.(2)Caprini model is more effective in evaluate the risk of VTE in surgery patients than medicine patients,and in predicting the risk of VTE recurrence,the Caprini risk assessment model is also be useful.