Clinical analysis of different CRRT in coronary heart disease patients complicated with chronic renal failure undergoing percutaneous coronary intervention

doi:10.3969/j.issn.1672-5301.2018.03.006

Abstract：Objective To analyze the different continuous renal replacement therapy (CRRT) in coronary heart disease patients complicated with chronic renal failure undergoing pereutaneous coronary intervention (PCI).Methods We performed a prospective study on 56 patients in our hospital from January 2016 to August 2017.All patients were divided into 2 groups:Normal group(CRRT did in first 12 hours after PCI treatment);Reinforcement group:CRRT did in 24 hours before and 12 hours after PCI treatment.Chronic health conditions,acute physiology,incidence of contrast-induced nephropathy(CIN) and serum creatinine were compared between the two groups.Results There was no significant difference in general information between general group and reinforcement group.CIN incidence in reinforcement group was significantly lower than the that in normal group(7.14％ vs.39.28％,P＜0.01).In the common group,the serum creatinine level at 24 hours after PCI was higher than that before PCI [(308.14±45.08)μmol/L vs.(254.59±80.44)μmol/L,P=0.02],while the serum creatinine level at 48 h and 72 h after PCI had no significant difference with that before PCI[(232.49±20.12)μmol/L vs.(247.52±54.81)μmol/L vs (254.59±80.44)μmol/L,P＞0.05].In reinforcement group,the serum creatinine level at 24 hours after PCI had no significant difference with that before PCI[(274.04±71.06)μmol/L vs.(286.65±53.04)μmol/L,P＞0.05],but the serum creatinine level at 48 h and 72 h after PCI was significantly lower than that before PCI [(220.12±23.87)μmol/L vs.(286.65±53.04)μmol/L,P=0.01],[(250.17±44.20)μmol/L vs.(286.65±53.00)μmol/L,P=0.02].Conclusion The effect of CRRT achieved both before and after PCI is better than CRRT only did after PCI,which has a positive effect on reducing the contrast-induced nephropathy.