Combination of GRACE score and TIMI-AF score to predict in-hospital and long-term mortality risk in patients with atrial fibrillation and acute coronary syndromes underwent percutaneous coronary intervention
Abstract：Objective To investigate the predictive value of GRACE score and TIMI-AF score for inhospital and long-term mortality in patients with atrial fibrillation and acute coronary syndromes underwent percutaneous coronary intervention (PCI).Methods A total of 2429 patients with atrial fibrillation and acute coronary syndromes underwent PCI in the Beijing area of 12 tertiary hospitals were enrolled,their GRACE scores and TIMI-AF scores were calculated,the in-hospital and long-term all cause death were observed,by comparing the area under the receiver operating curve(AUC),the predictive value of the two scores for mortality risk were assessed in the cohort.Results There were 34 deaths in the hospital,there were a total of 270 deaths who were followed up (3.19±l.52)years.To assess in-hospital death risk,the AUC of GRACE score was 0.826(P=-0.000),and the TIMI-AF score was 0.747 (P=0.000),no significant differences between the two scores.Combination of the two scores was 0.843 (P=0.000),no significant difference compared to GRACE,but better than TIMI-AF score.To assess long-term mortality risk,the AUC of GRACE score was 0.660 (P=0.000),and the TIMI-AF score was 0.659 (P=0.000),no statistical difference between the two groups.Combination of the two scores was 0.683 (P=0.000),superior to the single GRACE score or the TIMI-AF score.Conclusion In this cohort,GRACE score and TIMI-AF score can predict in-hospital and long-term risk of death,but their predictive value in the long-term risk was decline.The combination of the two scores can improve the ability to predict the long-term risk of death.
Keywords：Atrial fibrillationAcute coronary syndromesPercutaneous coronary interventionMortality riskPrediction model
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 136-141 )