Clinical significance of high sensitivity C-reactive protein in patients with acute myocardial infarction

WEI Rong-xin; HE Zong-yue; LI Hong

doi:10.3969/j.issn.1672-5301.2017.12.013

Abstract：Objective To investigate the clinical significance of detecting high-sensitivity C-reactive protein in early diagnosis of acute myocardial infarction.Methods 26 patients with acute myocardial infarction admitted in our hospital from August 2015 to August 2016 were selected as the experimental group.At the same time,26 normal subjects were selected as the control group.The levels of serum CK-MB,cTnI and hs-CRP were measured in the two groups.The differences of the three indexes were compared,and the positive rates of the two groups were compared.Results The levels of CK-MB,cTnI and hs-CRP in the experimental group were significantly higher than those in the control group (P＜0.01).The levels of CK-MB,cTnI and hs-CRP in the experimental group were significantly higher than those in the control group.The positive rate of CK-MB was 65.38％,the positive rate of cTnI was 61.54％ and the positive rate of hs-CRP was 92.31％,which were significantly higher than that of the control group (P＜0.01).The positive rate of hs-CRP in the experimental group was significantly higher than that in CK-MB and cTnI(P＜0.01),and the difference was statistically significant(x2=5.6497,P＜0.05;x2=6.9333,P＜0.01).The level of CK-MB,cTnI and hs-CRP increased gradually after 6 hours of chest pain,CK-MB and cTnI were the highest at 24 h,then decreased gradually,and the level of hs-CRP reached the highest at 72 h Gradually decreases.Conclusion The level of hypersensitive C-reactive protein is related to the occurrence of acute myocardial infarction.The detection of high-sensitivity C-reactive protein is of great clinical significance in the early diagnosis of acute myocardial infarction.