Clinical efficacy of recombinant human brain natriuretic peptide in the treatment of heart failure in eastern Inner Mongolia
Abstract：Objective To investigate the clinical efficacy of recombinant human brain natriuretic peptide (rhBNP) in the treatment of heart failure in the eastern part of Inner Mongolia.Methods From November 2015 to September 2016,110 patients with heart failure were chosen from Affiliated Hospital of Chifeng College.According to the treatment plan,the patients were randomly divided into two groups:observation group treated with rhB-NP(n=55) and the control group treated with nitroglycerin (n=55).The clinical efficacies of the two groups were compared and their influence in improving cardiac function were observed.Results In observation group,the total effective rate was 91％,which was higher than the control group (effective rate,67％)(P＜0.05).In observation group,the NT-proBNP was decreased significantly,there was significant difference between the two groups[the control group (5900±113.4)pg/ml vs observation group (3249±113.4)pg/ml,P＜0.05].Conclusion The clinical efficacy of rhBNP in the treatment of heart failure is effective,and it is worthy of popularization and application in Chifeng District of Inner Mongolia.
Keywords：Recombinant human brain natriuretic peptide (rhBNP)NitroglycerinHeart failureNT-proBNP
Publication Date：2017-01-01
Pages：3( 1033-1035 )