Study of the effects of blood pressure on the flow of grafts during off-pump coronary artery bypass grafting surgery
MA Shen
SU Pi-xiong
Abstract：Objective To explore the effects of the blood pressure to the blood flow of grafts in the offpump coronary artery bypass grafting.Methods Prospective analysis 31 patients that were selected randomly from August,2016 to October,2016 to cure heart disease by off-pump coronary artery bypass grafting,aged from 44 to 80 years old,21 among which were males,10 were females.These patients were either with angina or acute myocardial infarction.Preoperative examination has no obvious operation contraindications.The Transit-time Flow Measurements (TTFM),ECG monitor and cardiac output monitor were used to measure and record each related index,such as systolic blood pressure,diastolic blood pressure and mean arterial blood pressure,and pulmonary arterial blood pressure,central venous pressure,heart rate,Pulsation index and the blood flow of the grafts.Results Diastolic blood pressure has an obvious effect to the blood flow of the left anterior descending grafts (P=0.818,r2=0.669),the right coronary grafts(P=0.674,r2=0.469) and the left circumflex grafts(P=0.817,r2=0.669).However,the effect of systolic blood pressure to the blood flow of the left anterior descending branch grafts(P=0.685,r2=0.469),the right coronary grafts(P=-0.637,r2=0.417) and the left circumflex grafts(P=0.780,r2=0.610)were significant.Systolic blood pressure had little effect on the blood flow of left anterior descending artery.This was consistent with the records of blood flow image,but not match the Poiseuille flow formula.In addition to the above factors,self adjustment and myocardial systolic activity may be the reasons associated with coronary blood flow.Conclusion The diastolic blood pressure has a significantly influence to the three main branches of the coronary artery.However,systolic blood pressure have different effects on the flow of each grafts.To know how and why the blood pressure influences the flow of the grafts is vital for improving the quality of coronary artery bypass surgery,avoiding perioperative myocardial infarction and other complications,and the postoperative treatment and long-term management.
Keywords：Off-pump coronary artery bypass grafting (CABG)Transit-time flow measurements (TTFM)Blood-flow of graftsBlood pressure
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 985-990,后插1 )