The perioperation change of plasma brain natriuretic peptide in children with congenital heart disease combined pulmonary hypertension
Abstract：Objective To study the perioperation change of plasma brain natriuretic peptide (BNP) in children with congenital heart disease combined pulmonary hypertension.Methods 60 cases with left to right shunt congenital heart admitted in Inner Mongolia medical university affiliated hospital from December 2013 to December 2014 were enrolled.The pulmonary artery systolic pressure was evaluated by the echocardiography,and the different degree PAH plasma,BNP levels before and after surgery were compared.Results The blood plasma BNP levels in preoperative and seventh day of postoperative were rised with the increasing severity of PAH,and there were statistical significance among the absence of PAH,mild,moderate and severe PAH patients (P＜0.05).In preoperative and postoperative 7th day,the level of BNP was no statistical significance in the severe pulmonary hypertension group,but in the other three groups there were statistical significance (P＞0.05).Conclusion The level of plasma BNP increases with increasing of PAH in children with congenital heart disease combined pulmonary hypertension,and may be used as an evaluation of the degree of PAH.
Keywords：Brain natriuretic peptideCongenital heart diseasePulmonary arterial hypertensionClinical significance
Publication Date：2017-01-01
Pages：4( 829-832 )