Effects of thrombus aspiration on Tp-e and Tp-e/QT ratio in acute ST segment elevation acute myocardial infarction(STEMI) patients who underwent primary percutaneous coronary intervention
LUO Jin
LI Shao-nan
LUO Yi
Abstract：Objective To investigate the effect of thrombus aspiration on Tp-e and Tp-e/QT ratio in acute ST segment elevation acute myocardial infarction(STEMI) patients who underwent primary percutaneous coronary intervention.Methods 110 patients who were admitted to the hospital underwent PCI within 12 hours after onset of acute STEMI and randomly divided into thrombus aspiration group (thrombus aspiration+PCI) and control group (simple PCI).The Tp-e and Tp-e/QT ratio in the ECG in each patient was calculated before and after 2 hours PCI.Observed high risk ventricular arrhythmia(VA) in two groups during hospitalization.Results The gender,age,cardiovascular risk factors,symptom-onset-to-balloon time,Tp-e and Tp-e/QT ratio before PCI and so on have no significant differences between two groups.The ratio of ST-segment resolves (STR) greater than 70％,the reduction of Tp-e and Tp-e/QT ratio after PCI in thrombus aspiration group are higher than the control group[60.00％ vs 40.00％,(22.66±9.91)ms vs (15.89±8.24)ms,0.04±0.03 vs 0.03±0.02,P＜0.05].The Tp-e and Tp-e/QT ratio after PCI in thrombus aspiration group are lower than the control groups;and is also the occurrence of high risk VA during after PCI to discharge period[(88.54±13.13)ms vs (93.71±11.00)ms,0.25±0.03 vs 0.26±.0.03,16.00％ vs 33.33％,P＜0.05].Multivariate logistic regression analysis showed that thrombus aspiration was a protective factor in high-risk ventricular arrhymia during after PCI to discharge period.Conclusion Thrombus aspiration can reduce more ventricular repolarization dispersion index Tp-e and Tp-e/QT ratio in patients with STEMI who underwent primary PCI,and reducing the risk of high-risk ventricular arrhythmia.The reason may be thrombus aspiration is helpful to recover the microcirculation reperfusion.
Keywords：ST-elevation myocardial infarctionPercutaneous coronary interventionThrombus aspirationTp-eTp-e/QT ratio
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 702-706 )