Early routine post-prourokinase thrombolysis percutaneous coronary intervention vs primary PCI in ST-segment elevated myocardial infarction: a comparative study
Abstract：Objective Compare the efficacy early routine post-prourokinase thrombolysis percutaneous coronary intervention(early PCI) with primary percutaneous coronary intervention(PPCI) for acute ST-segment elevated myocardial infarction (STEMI).Methods In January 2014 June 2015,69 patients were treated with STE-MI in our hospital.The patients were divided into early PCI group and primary PCI group.The incidence rate,complication rate,mortality rate,and left ventricular ejection fraction (LVEF) were compared between two groups.Results 32 patients in early PCI group and 37 in PPCI group were finally included.87.9％ with early PCI group (18.7％ Thrombolysis in myocardial infarction trial TIMI-2,68.8％TIMI-3),and 18.9％ with primary PCI group (10.8％ TIMI-2,8.1％TIMI-3)(P＜0.01).The blood flow rates were similar in the two groups after PCI operation,90.6％(early PCI group),and 89.8％(primary PCI group)(P=0.653),but the number of stents used in the early PCI group was less in primary PCI group.There was no significant difference in the incidence of adverse events in the two groups during hospitalization (major bleeding,acute left heart failure,and length of hospital stay).After 1 months of follow-up,there were no significant differences in LVEF,LVEDd,cardiac death,myocardial infarction again,and stroke.Conclusion Early routine post-prourokinase thrombolysis PCI is an effective and safe reperfusion therapy strategy.
Keywords：Acute ST-segment elevation myocardial infarctionThrombolysisPercutaneous coronary interventionProurokinase
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 433-436 )