Sex difference in clinical profiles and quality of care among patients with ST-elevated myocardial infraction in Eastern Urban China from 2001 to 2011:the China PEACE-Retrospective Acute Myocardial Infarction Study
Abstract：Objective To investigate whether the sex differences in STEMI treatment patterns and outcomes were related to regional economic development,and how these sex differences have changed during the tenyear development in the most develop areas in China.Methods The study randomly selected a representative sample of patients admitted for STEMI in 2001,2006 and 2011,from urban hospitals in Eastern China.After central data abstraction from medical records,the study examined sex differences in patient profiles,treatment patterns and outcomes.Results Among 4742 patients with STEMI,30.5％ were female,with no significant change from 2001 to 2011.The median age of female patients increased from 68 years in 2001 to 71 years in 2011(P=0.003),while the median age of male patients decreased from 64 years in 2001 to 61 years in 2011 (P=0.029).Among those without contraindications,reperfusion (48.7％ vs 61.7％,P＜0.01) and primary percutaneous coronary intervention(PCI)(22.1％ vs 31.9％,P＜0.01) were less commonly used in female patients,as well as for non-primary PCI(14.8％ vs 20.2％,P＜0.01) and cardiac catheterization(34.1％ vs 49.0％,P＜0.01).Female patients had higher in-hospital mortality compare with male (14.2％ vs 6.6％,P＜0.01),which was consistent across the ten-year period.Conclusion Even in Eastern urban,the most developed areas in China,female patients with STEMI were less likely to receive evidence-based therapies,and suffered poorer outcomes,compared with their male counterparts.Understanding the reasons for this sex disparity and addressing these differences in care should be a priority in quality improvement.
Keywords：SexAcute myocardial infarctionQuality of care
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 310-316 )