Study on the degree of reperfusion injury after thrombolysis and interventional therapy in patients with gastric ulcer with ST segment elevation myocardial infarction
SUN Wen-heng
WU Chuan-jia
Abstract：Objective Based on the ST elevation myocardial infarction(STEMI)patients with ST segment elevation myocardial infarction patients with gastric ulcer and non gastric ulcer (control group)were observed. To investigat the differences of ischemia reperfusion injury and its mechanism of thrombolysis and interventional thera-py the two groups of after of differences were summed up. Methods The patients admitted in Jilin Central Hospi-tal and Department of Cardiology and Affiliated Hospital of Beihua University during 2014-2016 were divided into GU(gastric ulcer,n=40)group and control group(n=40),and two groups were accepted the same basic treatment for 2 weeks. Results ⑴The two groups by comparison showed that GU patients with myocardial coronary artery interventional therapy and thrombolytic therapy of superoxide dismutase (SOD)(390 ±17)U/g,catalase(CAT) (1399±90)KU/L,creatine kinase(CK)(500±50)U/L,showed no significant difference in the activity,and better than the control group CK (758 ±20)U/L,SOD (351 ±18)U/g,CAT (1100 ±30)KU/L,P<0.05. ⑵GU group showed increased gastrin (49.56±11.49)ng/L can ameliorate ischemia reperfusion injury,and the decrease of my-ocardial enzyme level (500±50)U/L effects are better than the control group. Conclusion Gastrin can effectively alleviate myocardial ischemia reperfusion injury in patients with ST segment elevation myocardial infarction.
Keywords：Gastric ulcerGastrinST segment elevation myocardial infarctionReperfusion injuryMyocardial protection
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 252-255 )