Observation of clinical effects on heart rate variability of new living factor on the old heart failure patients with diabetes

ZUO Quan; WANG Xin; CHEN Zhi-jun

doi:10.3969/j.issn.1672-5301.2017.02.020

Abstract：Objective To observe frozen rhBNP on chronic heart failure complicated with diabetes in elderly patients with heart rate variability of the impact and effectiveness and safety.Methods Diagnosed 60 cases of type 2 diabetes in elderly patients were randomly divided into chronic heart failure combined for two groups:the control group according to the chronic heart failure and diabetes guidelines based therapy and effectively control blood glucose treatment,the intervention group on the basis of the treatment combined static and new live prime,watch of the patients in the two groups,heart rate variability (HRV) change and heart failure relief degree,left ventricular diastolic diameter (LVDD),left ventricular ejection fraction,6 minutes walk test,N terminal pro-B-type natriuretic peptide precursor,24 hours urine volume changes.Results Degree of intervention group chest condition improved and left ventricular end-diastolic diameter,left ventricular ejection fraction,n-terminal b-type natriuretic peptide precursor is much better than the control group;6 min walking distance intervention group and control group after treatment(468± 123)m,respectively(390± 124)m.Urine intervention group and control group respectively for 2680 ml,2130 ml,differences between the two groups was statistically significant (P＜0.05).Two groups of patients with heart rate variability are lower,frequency domain power 24 h after treatment,SDANN (RR period average standard deviation between every 5 minutes) intervention group (2244± 1480)ms,respectively (42.5±16.1)ms,and the control group,respectively (2006±1632)ms,(32.2±18.6)ms,ms differences between the two groups was statistically significant(P＜0.05).Two groups have no adverse reaction occurred.Conclusion The new active elements can effectively improve the elderly patients with chronic heart failure and diabetes symptoms,can repair the patients with autonomic nervous damage,safe and effective.