Analysis on the Disease Burden Trends for Liver Cancer in China during 1990-2021

Xu Aolun; Ding Hao; Zhai Tie-min

Abstract：Objective:To analyze the disease burden of liver cancer and its changing trends in China from 1990 to 2021,so as to provide support for optimizing policies related to the prevention,control and treatment of liver cancer.Methods:Using the data from the Global Burden of Disease Study 2021,a descriptive analysis was conducted on the mortality and disease burden of liver cancer among different genders and age groups in China from 1990 to 2021.Joinpoint Software was used to estimate the average annual changes in the incidence rate,prevalence rate,mortality rate and DALY rate of liver cancer,as well as the annual percentage changes of each index in different time periods,so as to analyze the changing trends of the disease burden of liver cancer in China.Results:In 2021,the prevalence rate of liver cancer in China was 13.29 per 100 000,the incidence rate was 9.52 per 100 000,the mortality rate was 8.53 per 100 000,and the DALY rate was 239.91 per 100 000.From 1990 to 2021,the age-standardized prevalence rate of liver cancer in China increased by an average of 0.02％per year,while the incidence rate,mortality rate and DALY rate decreased by an average of 0.31％,0.79％and 1.03％per year respectively.The incidence rate,prevalence rate,mortality rate and DALY rate of males were all higher than those of females.Conclusion:From 1990 to 2021,the age-standardized DALY rate of liver cancer in China showed a downward trend,and the decline rate was faster than the global level.Interventions on excessive alcohol consumption,smoking and drug abuse should be further strengthened.