The Construction of Disease-Specific Reference Models and the Impact on Health Decision-Making
Pan Jie
Zhu Wentao
Guan Haijing
Abstract：As a tool for evaluating the value of drugs,Economic Evaluation(EE)models are playing an increasingly important role in healthcare and reimbursement decision-making in China.However,the lack of transparency and the uncertainty surrounding the results of these EE models have significantly hindered the translation of research evidence into policy decisions.Constructing a disease reference model provides a critical approach to address these challenges.First,starting from the concept of disease reference model,it compares its differences with traditional economics evaluation models and analyzes the key steps involved in their construc-tion;secondly,it takes advanced lung cancer,diabetes mellitus,and osteoporosis as typical cases to illustrate the main features and the current development of disease reference models;and it finally analyzes the advantages and challenges of the development of disease reference models in China.By systematically reviewing the methods and applications of disease reference models,it con-tributes to the exploration of future directions for economic evaluation models and promotes the high-quality development and deci-sion-making translation of pharmacoeconomics in China.
Keywords：pharmacoeconomicsdisease-specific reference modelshealthcare and reimbursement decision-makingevi-dence research
Publication Date：2025-03-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 9-14 )