The Measurement of Disutility of Hypoglycemia on Health-related Quality of Life in Patients with Diabetes:Based on Time Trade-off Survey
Yin Yichi
Shi Zhao
Li Shunping
Abstract：Objective:Evaluating the impact of various hypoglycemic events on the Health-Related Quality of Life(HRQoL)of diabetes patients to provide empirical data for health technology assessment.Methods:The data was collected from a tertiary hospital in Jinan,Shandong Province,China.Health utility was measured using the Time Trade-off(TTO)method,and disutility was calculated based on the formula.Subsequently,the intergroup differences among various hypoglycemic event groups were analyzed.Results:The hypoglycemic events'average utility was all lower than the average utility for diabetics without hypoglycemic events(baseline status).Severe hypoglycemic events(0.108)had higher disutility compared to non-severe hypoglycemic events(0.008).Furthermore,nocturnal severe/non-severe hypoglycemic events(0.118/0.008)exhibited higher average disutility than daytime severe/non-severe hypoglycemic events(0.098/0.007).Conclusion:Optimal diabetes management demands prioritizing the prevention of both severe hypoglycemic events and nocturnal hypoglycemic events.
Keywords：diabeteshypoglycemic eventstime trade-offdisutility
Publication Date：2024-06-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 64-67 )