Astrocyte-mediated immune evasion mechanisms in glioblastoma and targeted intervention
Abstract：Glioblastoma (GBM) is the most common and malignant primary brain tumor, with a 5-year survival rate below 10%. Current treatments are limited, and the immunosuppressive tumor microenvironment is the core reason for insufficient therapeutic response [1]. Astrocytes, as the most abundant cells in the central nervous system, have important immune regulatory functions, but their specific roles in GBM immune responses have remained unclear for a long time.
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Publication Date：2025-10-20
Online Publishing Date：2025-12-01(First online date of this platform, not the publication date of the document)
Pages：1( 630 )