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Local Delivery of Chlorotoxin-Embedded Chimeric Antigen Receptor Cells for the Treatment of Recurrent Glioblastoma: Early Safety and Disease Control
Abstract:Glioblastoma (GBM) is a common and highly invasive central nervous system malignant tumor, characterized by a unique immunosuppressive tumor microenvironment [1]. Although chimeric antigen receptor (CAR-T) cell therapy has achieved breakthrough progress in the treatment of hematological malignancies, its efficacy in GBM remains limited.
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Publication Date:2025-10-20
Online Publishing Date:2025-12-01(First online date of this platform, not the publication date of the document)
Pages:1( 629 )