Analysis of the role of intraoperative ultrasonography in glioblastoma resection
Guo Shaochun
Wang Yuan
Ji Peigang
Kou Yunpeng
Liu Jinghui
Han Yu
Li Xiaoqin
Qiang Xiaopeng
Wang Jia
Wang Liang
Abstract：Objective To explore the value of intraoperative ultrasonography in the resection of glioblastoma(GBM).Methods The clinical data of 136 patients with GBM were analyzed retrospectively.Intraoperative ultrasonography was used to assist in the surgical resection of GBM in all patients.Information on tumor location and size,preoperative and postoperative MRI results,intraoperative ultrasonography findings,postoperative pathological results,and follow-up information were collected.By comparing intraoperative ultrasonography data with postoperative MRI,the extent of tumor resection and the presence of residual tumor were determined.Results There were 114 cases in the total tumor resection group and 22 cases in the residual tumor group(residual tumors).Compared with the total tumor resection group,the preoperative tumor volume of the patients in the tumor residual group was larger(P<0.001).There were significant differences in progression-free survival(PFS)and overall survival(OS)between the two groups,with the PFS(7 months vs.4 months,P=0.013)and OS(12 months vs.7 months,P=0.008)significantly longer in the total tumor resection group.Further analysis showed that the total resection rate of intraoperative ultrasound-assisted GBM was 78.68%,and the correct judgment rate of residual tumor was 73.08%,and the residual tumor volume shown by postoperative MRI showed a high correlation(R2=0.9392).Conclusion The use of intraoperative ultrasound can help GBM patients achieve higher tumor resection rate,less tumor residual and longer survival time.
Keywords：glioblastomaultrasonographyintraoperativedegree of excisionefficacy analysis
Publication Date：2025-01-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 31-37 )