Preliminary exploration of ultrasonic dynamic monitoring of optic nerve sheath diameter changes for early diagnosis of acute high altitude cerebral edema
Zhang Jianbo
Zhang Yunyun
Bai Hongmin
Wei Linjie
Abstract：Objective To investigate the feasibility of using ultrasonic monitoring of optic nerve sheath diameter(ONSD)to guide the treatment of acute high altitude cerebral edema(HACE).Methods ONSD was measured by ultrasound in 40 healthy adult males who had recently arrived at high altitudes(control group)and 3 patients with acute HACE(HACE group).An ONSD threshold greater than 5.2 mm was used to diagnose increased intracranial pressure.ONSD was dynamically monitored during treatment and one week after discharge.Results The mean binocular ONSD in control group was(5.05±0.04)mm.The mean binocular ONSD in HACE group at the time of emergency consultation was(5.62±0.06)mm,(5.00±0.17)mm at the time of discharge after treatment,and(5.01±0.10)mm during follow-up after discharge.Compared with the control group,the mean ONSD in HACE patients at the time of emergency consultation was statistically significant(P<0.01),while there was no significant statistical difference in ONSD at the time of discharge and follow-up(P>0.05).The mean ONSD in HACE patients at the time of discharge and follow-up was significantly lower than that at the time of emergency consultation,with a statistically significant difference(P<0.05).Conclusions Ultrasonic monitoring of increased ONSD is a convenient,simple,and noninvasive method for diagnosing acute HACE,which has important clinical significance for the treatment of acute HACE.
Keywords：cerebral edemaacuteoptic nerve sheathplateauultrasonic dynamic monitoring
Publication Date：2024-07-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 392-395 )