Factors influencing the prognosis of elderly patients with ruptured intracranial aneurysms
Liu Yuanqi
Wei Zhenqing
Abstract：Objective To analyze the potential risk factors that may affect the prognosis of elderly patients with ruptured intracranial aneurysms.Methods The clinical data of 281 elderly patients(aged over 65)with ruptured intracranial single aneurysms,all of whom underwent either microsurgery or interventional embolization,were analyzed retrospectively.The modified Rankin Scale(mRS)was utilized to assess prognosis,with scores of 0-2 indicating good prognosis and 3-6 indicating poor prognosis.Results After a 2-year follow-up,216 patients were categorized into the good prognosis group,and 65 patients into the poor prognosis group.Statistically significant differences were observed between the two groups in age,hospital stay,Hunt-Hess grade,intraventricular hemorrhage,cerebral vasospasm,surgical factors(approach,timing,and duration),intraoperative blood loss,and postoperative complications(hydrocephalus,intracranial infection,lung infection,and neurological symptoms)(all P<0.05).Independent risk factors for prognosis included operative time(OR=1.723,95%CI:1.115-2.662),hydrocephalus(OR=3.907,95%CI:1.768-8.636),intracranial infection(OR=3.383,95%CI:1.189-9.624),lung infection(OR=10.157,95%CI:4.371-23.604),and Hunt-Hess grade(OR=2.139,95%CI:1.373-3.334).Conclusions The factors influencing the prognosis of elderly patients with ruptured intracranial aneurysms are complex,including age,Hunt-Hess grade,intraventricular hemorrhage,cerebral vasospasm,surgical factors(approach,timing,and duration),intraoperative blood loss,and postoperative complications.Among these,Hunt-Hess grade,hydrocephalus,intracranial infection,lung infection,and operative time have a substantial impact on prognosis.
Keywords：intracranial aneurysmagedrisk factorsprognosis
Publication Date：2024-06-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 352-358 )