A single-center case-control study on surgical and conservative treatments for supratentorial hypertensive intracerebral hemorrhage
Lian Shikun
Chen Zhisheng
Chen Zhihe
Tan Shaotao
Lan Xichang
Liang Fuhua
Gao Han
Abstract：Objective To investigate the efficacy of surgical and conservative treatments for supratentorial hypertensive intracerebral hemorrhage(HICH).Methods The clinical data of 465 patients with supratentorial HICH including 240 with conservative treatment(conservative group)and 225 surgical treatment(surgical group),were analyzed retrospectively.Binary logistic regression analysis was first applied to identify independent risk factors for ultra-early death within 7 days.Propensity score matching was then used to select 90 patients from each group for comparison.Kaplan-Meier survival analysis was employed to assess survival time between the two groups.While modified Rankin Scale(mRS)scores at 3,6,and 12 months post-onset,the incidence of complications,hospital stay and hospitalization costs during the inpatient period were compared.Results The average survival time of the surgical group was significantly longer than that of the conservative group(P=0.020).There were no significant differences in mRS scores between the two groups at 3,6,and 12 months post-onset.The surgical group had significantly longer hospital stays(P=0.005)and higher hospitalization costs(P<0.001)compared to the conservative group.In terms of complications,the surgical group had significantly higher incidences of pneumonia,urinary tract infections and gastrointestinal bleeding(P<0.05).Conclusions Surgical treatment may have a positive impact on survival time for patients with supratentorial HICH,but there were no differences in mRS scores at 3,6,and 12 months post-onset compared to conservative treatment.Additionally,surgical treatment is associated with longer hospital stays,higher hospitalization costs,and increased incidences of certain complications.
Keywords：intracerebral hemorrhagehypertensivesupratentorialsurgical treatmentconservative treatmentclinical efficacy
Publication Date：2024-06-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 345-351 )