Analysis of clinical features and risk factors of poor prognosis in acute ischemic stroke patients undergoing interventional thrombectomy

Zhang Peng; Wang Yufeng; Wang Long; Lu Linya; Zhang Yongsen

doi:10.11850/j.issn.1009-122X.2024.05.004

Abstract：Objective To analyze the clinical features and risk factors of poor prognosis in acute ischemic stroke(AIS)patients undergoing interventional thrombectomy.Methods The data of 172 patients with AIS,and all of them underwent interventional thrombectomy,were analyzed retrospectively.After 3 months of follow-up,these patients based on the prognosis were divided into 69 cases in the poor prognosis group(mRS 3-5 points)and 103 cases in the good prognosis group(mRS 0-2 points)according to the modified Rankin scale(mRS).Univariate and multivariate logistic analyses were used to study the clinical features and risk factors of poor prognosis after interventional thrombectomy in AIS patients.Results After 3 months of postoperative follow-up,there were 69 cases in the poor prognosis group,with an incidence rate of 40.12%.Compared with the good prognosis group,the poor prognosis group had a higher proportion of age>60 years,longer time from onset to admission,and higher preoperative National Institutes of Health Stroke Scale(NIHSS)score,preoperative Alberta stroke program early CT(ASPECT)score,number of thrombectomy,and blood glucose and homocysteine(Hcy)levels at admission(all P<0.05).The results of multivariate logistic analysis showed that the risk factors for poor prognosis of AIS-interventional thrombectomy included prolonged time from onset to hospital admission,increased NIHSS score,ASPECT score,and blood glucose level(OR was 1.813,1.990,1.782,and 2.335 respectively,all P<0.05).Conclusions The risk factors for poor prognosis of AIS patients undergoing interventional thrombectomy include prolonged time from onset to hospital admission,elevated NIHSS score,ASPECT score,and blood glucose level,thus screening the patients who have low risk factors for intervention and making the preventive measures pertinently for improving the prognosis of the patients.