Meta-analysis of the comparison in safety between nasojejunal tube and nasogastric tube for enteral nutrition in patients with severe traumatic brain injury
Xie Liping
Su Long
Li Qiang
Zhang Haiping
Lin Tao
Abstract：Objective To evaluate and compare the safety of nasojejunal tube(NJT)and nasogastric tube(NGT)for enteral nutrition in patients with severe traumatic brain injury by a meta-analysis.Methods A literature search was conducted from January 1950 to August 2023 in databases including Medline,EMBase,Cochrane Library,China National Knowledge Infrastructure(CNKI),and Wanfang Database.Studies related to the application of NJT and NGT for enteral nutrition in patients with severe traumatic brain injury were screened and selected.Meta-analysis was performed using Review Manager 5.4.1.Results A total of 30 studies involving 2952 patients were included.Meta-analysis showed that:① The pooled odds ratio(p OR)of vomiting and reflux in the NJT group compared to the NGT group was 0.21,with a 95%confidence interval(CI)of(0.16,0.28),and the difference between the two groups was statistically significant(P<0.01).②The p OR of aspiration rate in the NJT group compared to the NGT group was 0.23,with a 95%CI of(0.16,0.34),and the difference between the two groups was statistically significant(P<0.01).③The p OR of diarrhea rate in the NJT group compared to the NGT group was 0.66,with a 95%CI of(0.52,0.84),and the difference between the two groups was statistically significant(P<0.01).④ The p OR of gastrointestinal bleeding rate in the NJT group compared to the NGT group was 0.65,with a 95%CI of(0.48,0.86),and the difference between the two groups was statistically significant(P<0.01).⑤ The p OR of pulmonary infection rate in the NJT group compared to the NGT group was 0.30,with a 95%CI of(0.23,0.40),and the difference between the two groups was statistically significant(P<0.01).Conclusion Compared to NGT,NJT exhibit higher safety during enteral nutrition in patients with severe traumatic brain injury.
Keywords：brain injuryiestraumaticseverenasaljejunal tubenasogastric tubeenteral nutrition
Publication Date：2024-02-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 94-101 )