Effect of spinal nerve root pulsed radio frequency in treating patients with refractory radicular neuralgia
Jin Qi
Yang Tianshu
Abstract：Objective To explore the effect of spinal nerve root pulsed radio frequency(PRF)in treating refractory radicular neuralgia caused by lumbar disc herniation(LDH).Methods A total of 106 patients with refractory radicular neuralgia caused by LDH were divided into the experimental group and the control group by random number table method with 53 patients in each group,receiving conventional drug treatments and spinal nerve root PRF,respectively.Both groups were treated for 4 weeks.Curative effect,pain degree,degree of lumbar dysfunction,serum indicators and adverse reactions were compared between groups.Results The rate of excellent and good treatment result in the experimental group was higher than that in the control group(P<0.05).After treatment,the Numerical Rating Scale(NRS)scores in the experimental group were lower than those in the control group(P<0.05),and Japanese Orthopaedic Association(JOA)scores were higher than those in the control group(P<0.05).The levels of inflammatory factors such as tumor necrosis factor(TNF-α),interleukin-1(IL-1)and interleukin-6(IL-6),nitric oxide(NO)and prostaglandin E2(PGE2)in the experimental group were lower than those in the control group(P<0.05),and the level of superoxide dismutase(SOD)was higher than that in the control group(P<0.05).The incidence of adverse reactions were similar betwen the two groups(P>0.05).Conclusion Applying spinal nerve root PRF to treat refractory radicular neuralgia caused by LDH can effectively improve the excellent and good rate of curative effect,reduce the degree of pain and lumbar dysfunction,and improve related serum indicators,with good safety.
Keywords：lumbar disc herniationradicular neuralgiaspinal nerve rootpulsed radio frequencyserum indicator
Publication Date：2023-12-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 63-66 )