Deep brain stimulation with domestic equipment and different frequencies of left and right program control for the Meige syndrome
Zhao Quanjun
Wang Jia
Sun Bomin
Wang Wei
Jia Yunfeng
Wang Tao
Li Lianfeng
Bai Xiaojun
Cui Shaojie
Gu Jianwen
Abstract：Objective To determine the clinical outcomes of a Meige syndrome patient undergoing deep brain stimulation (DBS) with domestic stimulator and bilateral different frequency stimulation program. Methods The clinical data of 1 patient with Meige syndrome undergoing bilateral globus pallidus internus (Gpi) DBS operation was analyzed retrospectively. The routine stimulation was performed 1 month after the operation and different frequency stimulation was administrated 3 months postoperatively. Burke-Fahn-Marsden dystonia rating scale (BFMDRS) was used to evaluate the clinical outcome. Results The symptoms of the patient were significantly improved by the stimulation 1 month after the operation. The BFMDRS declined from 22 to 6. Since the right electrode contacts were near the posterior limb of the internal capsule, the voltage of stimulation was low and the patient felt numb of left limbs. The effect was obtained by increasing the voltage of the left electrode. The symptoms recurred a little 3 months after the operation and the BFMDRS was recovered to 10. The different frequency stimulations in the left and right sides were administrated with decrease of the stimulation frequency in the right side. The stimulation voltage in the right side was increased to improve the symptoms and in the left side was decreased in order to reduce the power consumption. The numb of left limbs disappeared and the symptoms further improved. BFMDRS was decreased to 4. Conclusions DBS with domestic stimulator at bilateral Gpi is satisfactory for the treatment ofMeige syndrome and different frequency stimulations in the left and right sides can decrease the side effect and increase the treatment effect further.
Keywords：Meige syndromedeep brain stimulationglobus pallidus internusdifferent frequency stimulation
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 223-225 )