Efficacy analysis of fractionated gamma knife treatment for cavernous sinus cavernous hemangiomas
Huang Minyi
Deng Yinhui
Liang shunyao
Abstract：Objective To investigate the effects of fractionated gamma knife treatment for cavernous sinus cavernous hemangiomas (CHs). Methods Clinical data of 11 patients with cavernous sinus CHs were analyzed retrospectively. The MRI characteristics of the tumors were as follows: T1WI showed hypointensity or isointensity, T2WI showed homogeneous hyperintensity, and enhanced scan showed homogenous enhancement. The maximum diameter of the tumors was 78 mm and the minimum was 40 mm. Fractionated Leksell gamma knife treatment ranging from 6 to 8 months was performed in all the patients. During the first treatment, the radioactive dose of tumor core was 25 Gy and the average dose of the tumor margin was 9 Gy. During the second treatment, the radioactive dose of the core was 30 Gy, and the average dose of the tumor margin was 15 Gy. Results The mean follow-up period was 36 months, ranging from 6 to 48 months. No patients showed any new cranial nerve deficits, and the initial symptoms were improved to different degrees. The tumor almost disappeared in 2 patients and significantly shrank in 9 in 6 to 12 months after gamma knife treatment based on the imaging finding. Conclusion Fractionated gamma knife treatment is well effective for cavernous sinus CHs.
Keywords：hemangiomascavernouscentral nervous systemcavernous sinusgamma-kniferadiosurgery
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 104-106 )