Clinical efficacy analysis of neuronavigation guided endonasal microsurgery for sellar region tumors via transsphenoidal approach
Li Yang
Xu Jian
Wang Yang
Zhao Dong
Liu Qi
Abstract：Objective To analyze the clinical effects of neuronavigation-guided endonasal microsurgery for sellar region tumors via transsphenoidal approach. Methods Clinical data of 37 patients with sellar region tumors were analyzed retrospectively, who were treated by neuronavigation-guided endonasal microsurgery via transsphenoidal approach. Results The pathological diagnosis were pituitary adenoma in 32 patients, Rathke cleft cyst in 4 and chordoma in 1. The follow-up period was 5 to 24 months with the mean period of 14 months. The tumors were totally removed in 28 patients, subtotally in 5 and partially in 4. The transient diabetes insipidus occurred in 5 patients who recovered by using pituitrin or Minirin. CSF leakage occurred in 1 patient who was cured by lumbar cistern drainage. Among the 24 patients with impaired vision, visual acuity was improved in 20, remained unchanged in 2 and aggravated in 2. Among the 19 patients with abnormal hormone level, endocrine remission was observed in 15, remained unchanged 3 and aggravated in 1. Conclusions The neuronavigation-guided endonasal microsurgery for sellar region tumors via transsphenoidal approach is a safe and effective method.
Keywords：pituitary neoplasmsneuronavigationendoscopemicroscopesellar regionapproachtranssphenoidal
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 448-450 )