Application of multimodal navigation and image fusion technology in neuroendoscopic surgery of pituitary adenomas via transsphenoidal approach
Han Peng
Li Xuqin
Yu Jun
Jin Dianshi
Luo Ke
Leng Xiaolei
Hu Yingjie
Abstract：Objective To explore the application values of multimodal navigation and image fusion technology in neuroendoscopic surgery of pituitary adenomas via transsphenoidal approach. Methods Clinical data of 47 patients with pituitary adenomas were analyzed retrospectively, and endoscopic surgery assisted with navigation via transsphenoidal approach was performed in all the patients. Before the operation, the thin-section CT scans of the sellar region were performed in all the patients, and brain MRA fusion in 40 patients and brain CTA fusion in 7. Results The lesions were accurately positioned by navigation in all the patients. Total tumor resection was achieved in 38 patients and subtotal resection in 9. Cerebrospinal fluid leakage occurred in 3 patients, infection in 1 and transient diabetes insipidus in 1 after the operation. No patient died and no bleeding occurred. During a follow-up period of 3 to 24 months, the preoperative symptoms were improved to different extents in most patients. Recurrence occurred in 3 patients of total resection and 1 in subtotal resection, andγ-knife treatment and resurgery were carried out respectively. Conclusions Neuronavigation and image fusion technique can provide three-dimensional structural images for the lesions and surrounding tissues. Combined with the good illumination and visual field of neuroendoscopy, it can increase the rate of total tumor resection, reduce pituitary dysfunction, shorten the operation time and reduce the complication.
Keywords：pituitary neoplasmsneuronavigationneuroendoscopymultimodal image fusion
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 322-325 )