A preliminary clinical study of intravoxel incoherent motion diffusion-weighted MRI in meningioma
Zhang Xin
Han Lixin
Zhang Li
Wu Youliang
Cao Huixia
Du Weiqing
Wang Jun
Lv Peifeng
He Nianbo
Abstract：Objective To evaluate the application value of the mono-exponential model and bi-exponential model of intravoxel incoherent motion diffusion-weighted MRI (IVIM-MRI) in meningiomas.Methods Twenty meningioma patients confirmed by surgical pathology were brought into this study,and received routine MRI and IVIM-MRI scan.The apparent diffusion coefficient (ADC) of mono-exponential model and the diffusion coefficient (D),pseudo perfusion coefficient (D*) and the perfusion fraction (f) of bi-exponential model were measured both in tumor and normal white matter (NWM) areas,then the IVIM-MRI feature of meningioma was analyzed.Results In mono-exponential model,ADC value was lower in the tumor area than in NWM area,but the difference was not statistically significant (t =0.514,P ＞ 0.05).In bi-exponential model,the difference in D value was statistically significant between tumor and NWM areas (t =3.043,P ＜ 0.01),while there was no significant difference in D* and f values between tumor and NWM areas (t =1.274,0.220,P ＞ 0.05).Otherwise,there were significant differences in ADC,D,f values between the four different pathological subtypes of meningiomas (F =5.232,5.674,14.058,P ＜ 0.01).Conclusion IVIM-MRI can get the accurate perfusion and diffusion informations of meningiomas,and can be considered as a noninvasive perfusion method for brain tumors.
Keywords：meningiomamagnetic resonance imagingintravoxel incoherent motiondiffusion weighted imagingperfusion
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 256-259 )