Diagnosis and treatment of pituitary adenomas in elderly patients
Ma Lin
Gao Lu
Guo Xiaopeng
Wang Qiang
Wang Zihao
Lian Wei
Wang Renzhi
Xing Bing
Abstract：Objective To explore the clinical,diagnosis and treatment characteristics of pituitary adenomas in elderly patients.Methods Clinical data of 110 elderly patients with pituitary adenomas were analyzed retrospectively.The tumor resection by surgery was performed on 101 patients and no surgery on 9.Results The tumors were totally resected in 91 patients,subtotally or partially resected in 9 and coagulative necrosis was seen in 1 patient.The pathological diagnosis was conducted as pituitary adenoma.Seventy-eight patients were followed up for 12 to 47 months and the symptoms were improved.The pituitary absess ocurred in 1 patient 4 months after surgery and improved by surgical treatment.The non-functioning pituitary adenomas and functioning pituitary adenomas were analyzed by MRI and hormone reexamination respectively.Relapse occurred in 3 of 51 patients undergoing surgery.Among the 5 patients who did not receive surgery,the tumor shrinked in 2 patients who received temozolomide and remained unchanged in 3.The postoperative symptoms were improved in the left 22 patients who did not periodically receive MRI and hormone reexamination.There was no death during the follow-up period.Conclusions The onset of pituitary adenoma is insidious in elderly patients.The pituitary MRI should be performed for early diagnosis when visual dysfunction symptoms appear.The tumor resection via transsphenoidal approach is credible in elderly patients after critical assessment of surgical risks.
Keywords：pituitary neoplasmsagedneurosurgical proceduresperioperative management
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 169-171 )