Surgical choice and skills of pituitary microadenoma resection via single nostril transsphenoidal approach
Li Lianjie
Gu Jianjun
Cheng Lan
Wei Liangfeng
Wang Shousen
Abstract：Objective To explore the surgical choice and skills of pituitary microadenoma resection via single nostril transsphenoidal approach.Methods Clinical data of 30 patients with pituitary microadenoma were analyzed retrospectively who underwent surgical resection via single nostril transsphenoidal approach.The resection was performed as extracapusularly as possible and tumor beds were treated moderately by electrocoagulation if necessary.The immunohistochemical examination revealed that there was prolactin adenoma in 8 patietns,adrenocorticotropic hormone (ACTH) adenoma in 7,growth hormone (GH) adenoma in 5,thyroid stimulating hormone (TSH) adenoma in 1,plurihormone-secreting adenoma in 5 and nonfunctioning adenoma in 4.Results Total resection was achieved in 28 patients,subtotal resection in 2 including 1 ACTH adenoma and 1 GH adenoma.All the patients were followed up for 4 months,hormone levels decreased to normal level in 23 patients,decreased more than 50％ in 2 and remained unchanged in 1.Thirty patients were followed up for 6 to 78 months and clinical symptoms were all improved to different degrees.Conclusions Symptomatic non-functional pituitary microadenoma can be treated by transsphenoidal surgery.Transsphenoidal surgery is effective for functional pituitary microadenoma.Accurate location and exposure of the tumor during operation and skillfull treatment of cavernous sinus hemorrhage are important prerequisites for total resection of pituitary microadenoma.
Keywords：pituitary neoplasmsapproachtranssphenoidaltypingimmunohistochemicalmicrosurgery
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 158-161 )