Clinical analysis of lumboperitoneal shunts for the treatment of idiopathic normal pressure hydrocephalus
Cai Yong
Zhong Xingming
Wang Yiqi
Yang Jianguo
Zhao Chaohui
Fei Zhenhai
Zhang Lei
Abstract：Objective To investigate the therapeutic effects and advantages of lumboperitoneal shunt (LPS) for the treatment of idiopathic normal pressure hydrocephalus (iNPH). Methods Clinical data of 33 iNPH patients treated by LPS were analyzed retrospectively. The main clinical features included gait disturbance, cognitive impairment and urinary incontinence, which were evaluated by 5-m Up&Go test, mini-mental state examination (MMSE) and questionnaire respectively. Positive cerebrospinal fluid (CSF) tap test was a prerequisite for surgical treatment. The changes of the ventricular system after surgery were assessed by Evan's index. Results After CSF tap test, positive results of 5-m Up&Go test were observed within 24 h in 21 patients and within 24 to 72 h in 12. During a follow-up period of 6 to 24 months after shunt, clinical systems improved in different degree in the most patients. The mean MMSE scores before and 6 months after shunt were 24.8±2.8 and 26.2±2.5 respectively, and the difference was significant (P<0.05). And the mean Evan's index before and 6 months after shunt was 0.39±0.04 and 0.38±0.04 respectively, the difference was not significant (P=0.3137). There were no death and complications such as postoperative infection and clogging of the shunt tube in this group. Conclusion LPS is a safe and effective therapy for iNPH with the advantages of minimal invasiveness, rapid recovery and fewer complications.
Keywords：hydrocephalusnormal pressureidiopathiclumboperitoneal shuntsmental status scheduleEvan's index
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 550-552 )