Application Progress of Viscoelastic Hemostatic Assay in Extracorporeal Membrane Oxygenation Anticoagulation Man-agement
LYU Zhu
WEN Junlin
FAN Xiaolan
LIU Hao
LIAO Xiaozu
LI Binfei
Abstract：Extracorporeal membrane oxygenation(ECMO)serves as an essential life-support intervention for critically ill patients.Despite its life-saving potential,ECMO is associated with a considerable incidence of hemorrhagic and thrombotic complications,which significantly compromise patient prognosis.Consequently,the accurate assessment of bleeding risk and precise management of anticoagulation and transfusion therapy have emerged as paramount clinical priorities.Viscoelastic hemostatic assay(VHA),which provides a dynamic,real-time profile of the hemostatic process,is being increasingly integrated into the anticoagulation management of ECMO patients due to its rapidity and comprehensive nature.This review systematically evaluates the correlation between VHA and conventional laboratory assays in the context of bleeding and anticoagulation monitoring,and critically appraises the evolving role of VHA in guiding ECMO anticoagulation.Focusing on clinical studies from the past 10 years,this review comprehensively evaluates the current applications and future directions of this technology in clinical practice,with the aim of providing a theoretical basis and practical guidance for anticoagulation management and transfusion strategies in ECMO patients.
Keywords：extracorporeal membrane oxygenationviscoelastic hemostatic assaythrombelastographyanticoagulation managementtransfusion
Publication Date：2026-02-28
Online Publishing Date：2026-03-20(First online date of this platform, not the publication date of the document)
Pages：6( 62-67 )