Comparative study of minimally invasive versus median sternotomy off-pump coronary artery bypass grafting based on propensity score matching
Zhao Linli
Zhang Bing
Yi Wei
Abstract：Objective To compare perioperative outcomes and prognosis between minimally invasive coronary artery bypass grafting(MICABG)and median sternotomy off-pump coronary artery bypass grafting(OPCABG)through a propensity score-matched observational cohort study.Methods Clinical data of CABG patients in our hospital were retrospectively collected.After applying inclusion and exclusion criteria,85 MICABG and 226 OPCABG group patients were enrolled.A 1:1 propensity score matching(PSM)was performed to balance baseline characteristics.Perioperative outcomes and major adverse cardiovascular and cerebrovascular events(MACCE)were compared,with subgroup analysis and survival analysis conducted to evaluate long-term prognosis.Results After matching,the MICABG group demonstrated significantly shorter operative times,reduced intraoperative blood loss,fewer drainage tubes and fewer grafted vessels compared to the OPCABG group(P<0.001).However,no significant differences were observed in the incidence of MACCE,all-cause mortality,non-fatal stroke,non-fatal heart failure,non-fatal myocardial infarction,wound complications,repeat revascularization,cardiac-related readmissions,in-hospital MACCE or in-hospital death between the two groups(all P>0.05).Conclusion MICABG is associated with reduced surgical trauma,faster recovery,and comparable long-term outcomes to OPCABG,suggesting its viability as a less invasive alternative for selected patients.There were no significant differences in prognosis between MICABG and OPCABG patients.
Keywords：Coronary artery bypass graftingMinimally invasiveOff-pumpSurvival analysisPrognosis
Publication Date：2025-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：9( 243-250,254 )