Recent advances and future perspectives in anticoagulation management for extracorporeal membrane oxygenation
Xu Enhui
Sun Qi
Lu Juan
Xiong Ying
Wei Xinguang
Liu Yan
Abstract：During extracorporeal membrane oxygenation(ECMO),the goal of anticoagulation management is to prevent thrombus formation within the circuit,oxygenator,and the patient's body,as well as minimizing bleeding complications.Bleeding and thrombosis are common complications in ECMO therapy and are significantly associated with increased mortality and adverse outcomes.Anticoagulation is essential for maintaining ECMO circuit patency and preventing thromboembolic complications but also contributes to bleeding complications.How to reduce bleeding while preventing thrombus formation has become one of the primary challenges in ECMO support.Therefore,monitoring coagulation status and implementing anticoagulation strategies during ECMO support are particularly critical.This article reviews the latest research progress on anticoagulation strategies and monitoring during ECMO and explores the challenges currently faced in ECMO treatment.
Keywords：Extracorporeal membrane oxygenationAnticoagulationComplicationsMonitoringAnticoagulation management
Publication Date：2025-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 176-180,185 )