Etiology analysis and management strategies for air embolism in circulatory systems during modified ultrafiltration
Guo Zheng
Zhang Wei
Shen Jia
Jiang Lei
Huang Jianhu
Wang Wei
Abstract：Objective To investigate the etiology of air embolism in circulatory systems during modified ultrafiltration(MUF)and to propose prevention measures and management strategies.Methods We conducted a retrospective analysis of air embolism events during cardiopulmonary bypass(CPB)at Shanghai Children's Medical Center over a 12-year period.Data on causative factors,management approaches,and clinical outcomes were systematically evaluated.Results Among 34,519 CPB procedures performed between January 2013 and August 2024,18 cases(0.05%)of air embolism during MUF were identified.Human factors accounted for 9 cases(8 perfusionist errors,1 surgical error),while technical factors comprised the remaining 9 cases,all attributed to arterial cannula orifice proximity to the vessel wall,leading to wall suction during MUF.Clinical outcomes included transient neurological complications in 3 patients and 1 mortality,with no significant sequelae in the remaining cases.Conclusion Air embolism during MUF primarily results from human error and arterial wall suction by cannula orifices.Implementation of comprehensive training programs for cannulation and emergency management,rigorous intraoperative verification protocols,enhanced surgeon-perfusionist communication,and timely equipment maintenance can significantly reduce air embolism risks.Prompt and appropriate management strategies are crucial for minimizing complications.
Keywords：Cardiopulmonary bypassModified ultrafiltrationAccidentCardiac surgery
Publication Date：2025-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 122-126 )