Preliminary design and in vitro durability testing of "chimney" mitral bioprosthetic valve
Bao Luri
Song Laichun
Dong Jincheng
Tao Liang
Abstract：Objective To design a novel mitral valve that offers a potentially valuable alternative for patients with mitral prosthesis-patient mismatch (PPM) and to preliminarily assess the feasibility and safety of this valve through durability testing. Methods According to the durability testing methods specified in the ISO 5840 standard,the valve was tested on a VDT-3600I heart valve fatigue testing machine for 300×106 cycles. Observations at 10x magnification were conducted on the test valve after 50 million,100 million,and 300 million cycles. Results TAO-4-001,TAO-4-002,and TAO-4-003 valves showed no damage at 10x magnification after 50×106,100×106,and 300×106 cycles,respectively. The "chimney" showed no significant stretching deformation,and its deformation range was acceptable throughout the test cycle. Conclusion "Chimney" Mitral Bioprosthetic Valve demonstrated stable mechanical motion and consistent performance characteristics under long-term load conditions,indicating its suitability for sustained clinical application.
Keywords：Mitral valveProsthesis-patient mismatchDurability testingIn vitro performance testingCardiac surgery
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 510-515 )