Comparison of veno-arterial extracorporeal membrane oxygenation timing in the perioperative period of percutaneous coronary intervention
Wang Jing
Bian Luyu
Li Zhenzhen
Liu Gang
Wang Jian
Wang Qian
Teng Yuan
Wang Tianlong
Zhang Han
Yan Shujie
Lou Song
Hu Qiang
Gao Guodong
Ji Bingyang
Abstract：Objective To assess the efficacy and safety of extracorporeal membrane oxygenation (ECMO) support timing during the perioperative period of percutaneous coronary intervention (PCI) in patients with myocardial infarction. Methods A retrospective analysis of patients who underwent PCI and received ECMO support at Fuwai Hospital from January 2018 to August 2022 was conducted,involving a total of 14 patients. Patients were divided into two groups based on the timing of ECMO initiation:the prophylactic ECMO support group (n=6) and the non-prophylactic ECMO support group (n=8). Clinical data,PCI treatment details,mechanical support,complications,and outcomes were collected. Results The mean age of the 14 patients was (57.9±13.3) years,with males accounting for 85.7％. The prophylactic ECMO support group mainly had triple vessel disease (66.7％),while the non-prophylactic ECMO support group mainly had single or double vessel disease (75％). The median number of stents and balloons inserted in the prophylactic ECMO support group was significantly higher than that in the non-prophylactic ECMO support group (3 vs. 1,P=0.005,6 vs. 2,P=0.020;respectively). The median duration of PCI was longer in the prophylactic ECMO support group compared to the non-prophylactic ECMO support group (109 min vs. 27 min,P=0.042). The mortality rate was significantly higher in the prophylactic ECMO support group compared to the non-prophylactic ECMO support group (75.0％ vs. 16.7％,P=0.031),with no significant difference in complications between the two groups. Conclusion Prophylactic ECMO support improves the revascularization rate and survival rate of myocardial infarction patients undergoing PCI,without increasing the risk of complications.
Keywords：Myocardial infarctionExtracorporeal membrane oxygenationPercutaneous coronary interventionCardiogenic shockCardiac arrest
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 365-370,399 )