Clinical significance and feasibility of real-time CO2 monitoring via air outlet of membrane oxygenator for evaluation of PaCO2
Duanmu Jianyu
Liang Yongnian
Yu Xiang
Du Lei
Xiong Jiyue
Abstract：PaCO2,which means the partial pressure of carbon dioxide(CO2)in arterial blood,is important in maintaining blood pH and regulating vascular tone.In physiological states,the body's chemoreceptors continuously receive PaCO2 signals and maintain PaCO2 within normal ranges through the lungs.During cardiopulmonary bypass(CPB),however,PaCO2 may be out of normal range,because of mechanical ventilation,artificial circulation,as well as usage of CO2 gas for covering the surgical field.Unfortunately,lack of physiological reflex during CPB would aggravate the abnormality of PaCO2 and thus the adverse effects occur,such as its adverse effect on the cerebral vessel.Therefore,real-time PaCO2 monitoring during CPB is significant,but not implemented due to the lack of equipment.Inspired by the real-time EtCO2 to evaluate PaCO2 during general anesthesia,real-time CO2 monitoring through the exhaust of membrane oxygenator(OeCO2)may be simple and feasible to evaluate PaCO2.However,OeCO2 can be affected by many factors.This review will focus on the real-time OeCO2 monitring and its significance,in the hope of improving the outcomes.
Keywords：Cardiopulmonary bypassPaCO2OeCO2
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 318-323 )