Outcomes of extracorporeal membrane oxygenation during the lung transplantation

Chen Guanying; Yu Fumin; Lin Zhonglin; Zhan Weifeng; Ben Xiaosong; Shu Haihua; Deng Yiyu; Zhou Chengbin

doi:10.13498/j.cnki.chin.j.ecc.2024.03.03

Abstract：Objective To investigate the outcomes of extracorporeal membrane oxygenation(ECMO)in lung transplantation.Methods A total of 44 patients who underwent lung transplantation in a single center from January 2019 to July 2023 were retrospectively analyzed,including 30 cases with ECMO before lung transplantation after anesthesia and 14 cases without ECMO during the operation.The general data,blood gas analysis results and hemodynamics of the patients were collected.The changes of pulmonary artery pressure before and after bypass were compared,and the outcomes of patients were analyzed.Results ECMO could improve intraoperative carbon dioxide retention and decrease intraoperative pulmonary artery pressure(P<0.05).At the end of the operation,6 cases were weaned from ECMO during the operation,and 24 cases were weaned from ECMO in ICU,with an average ECMO support time of 33.65 hours.There was one patient who did not use ECMO due to secondary pulmonary malignant tumor.The patient developed postoperative hypoxia and was placed on ECMO in the ICU.After 281.95 hours of ECMO support,the patient unfortunately died of severe infection during the support period.There was no significant difference in the volume of pleural fluid in 24 hours after operation,the length of ICU stay and the in-hospital mortality between the two groups of patients with and without ECMO during operation.Conclusion The application of ECMO during lung transplantation can remove carbon dioxide retention,reduce pulmonary hypertension,and does not increase blood loss,but it does not affect the prognosis of patients.