Analysis of risk factors of acute kidney injury during extracorporeal membrane oxygenation assistance
Xiong Wenfang
Yao Lan
Wang Hui
Han Qianpeng
Jiang Qinjuan
Abstract：Objective To investigate the risk factors of acute kidney injury(AKI)in patients treated with extracorporeal membrane oxygenation(ECMO).Methods Methods A retrospective study was performed on 31 patients who received ECMO in Yueyang Central Hospital of Hunan Province from November 2015 to January 2024 to explore the risk factors of AKI.The basic conditions of patients before ECMO and the relevant clinical conditions during ECMO were collected,and the patients were divided into non-AKI group and AKI group according to whether they developed AKI.Univariate analysis and logistic regression analysis were used to identify potential risk factors that may affect AKI.Results Univariate analysis showed that 16 patients(51.6%)with AKI were associated with pre-ECMO hyperhematocrit,initial ECMO flow,large-scale myocardial infarction,and cumulative days of positive fluid equilibrium.The results of multivariate analysis showed that hematocrit(OR 1.24,95%CI:1.027～1.488;P = 0.025)and cumulative days of positive fluid equilibrium during ECMO treatment(OR 2.23,95%CI:1.126～4.418;P = 0.021)were risk factors for AKI in ECMO patients.Conclusion Hematocrit and cumulative days of positive fluid equilibrium during ECMO treatment and hematocrit are risk factors for AKI in patients undergoing ECMO.
Keywords：Extracorporeal membrane oxygenationAcute kidney injuryRisk factorFluid management
Publication Date：2024-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 8-12 )