Research progress on the regulation of exosomes derived from different cell sources in ischemic heart disease
Xu Lulu
Zhou Chengbin
Abstract:Exosomes are nanosized membrane vesicles secreted by cells under both physiological and pathological con-ditions.The vesicles represent a novel machanism of intercellular communication by serving as mediators for transport between cells with cytosolic proteins,lipids,RNAs and other bioactive molecules.Several studies have showed that exosomes involve multiple stages in ischemic heart disease and play an important role in cardioprotection.In this review,the regulation of exosomes derived from cardiac cells and different stem cells in ischemic heart disease is summarized in order to provide new insight for both diagnostics and therapeutics of ischemic heart disease.
Keywords:ExosomesIschemic heart diseaseMyocardial infarctionCardioprotection
Publication Date:2023-12-28
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 381-384 )
