Clinical outcomes of adults with postcardiotomy cardiogenic shock undergoing venoarterial extracorporeal membrane oxygenation: A systematic review and meta-analysis
Shao Chengcheng
Wang Liangshan
Wang Hong
Hou Xiaotong
Abstract：Objective This study was designed to investigate the clinical outcomes of adults with postcardiotomy cardiogenic shock undergoing venoarterial extracorporeal membrane oxygenation. Methods We searched PubMed, Embase, Cochrane Library and other databases to find out relevant studies of postoperative ECMO patients for meta-analysis. Results Fourteen observational studies were selected for final analysis. The pooled mortality rate to hospital discharge was 66.0％ (95％ CI 0.61, 0.71) in PCS patients receiving ECMO. The pooled 1-year survival rate was 24％ (95％ CI 0.19, 0.30). The pooled midterm survival rate was 19％ (95％ CI0.10, 0.34). The pooled rate of lower limb ischemia was 14％ (95％ CI 0.10, 0.20). The pooled rate of reoperation was 44％ (95％CI 0.21, 0.70). The pooled rate of renal failure was 49％ (95％ CI 0.38, 0.61). The pooled rate of neurologic complications was 18％ (95％ CI 0.11, 0.29). The pooled rate of infection was 23％ (95％ CI 0.16, 0.31). Most of the included studies commonly revealed that age＞65 years, pre-ECMO or post-ECMO blood lactate, renal insufficiency, long duration of ECMO, and neurologic complications were risk factors of in-hospital mortality in PCS patients undergoing ECMO. Conclusion The short-term and midterm survival rates of PCS patients treated with ECMO were relatively low, and post-ECMO complication rates were relatively high. Many risk factors were related to in-hospital mortality.
Keywords：Extracorporeal membrane oxygenationPostcardiotomy cardiogenic shockMortality rateComplicationRisk factorMeta-analysisEvaluateClinical outcome
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 4-7,25 )